This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing.
More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.
CD68 Polyclonal Antibody | 544-MBS176833 Species Reactivity: Human Host/Isotype: Rabbit / IgG Class: Polyclonal Type: Antibody Immunogen: Synthetic peptide in the internal region of human CD68...
PSP Antibody | 88-30133-05161 Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal Prostate Secretory Protein/PSP -...