Anti-AAV Mouse Monoclonal Antibody | Gentaur

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Anti-AAV Mouse Monoclonal Antibody | 252-03-65157

Species Reactivity Virus

Published species Virus

Host/Isotype Mouse / IgG2a, kappa

Class Monoclonal

Type Antibody

Clone M58

Immunogen Adenovirus

Conjugate Unconjugated

Form Liquid

Concentration 0.2 mg/mL

Purification Protein A

Storage buffer PBS, pH 7.4, with 0.2% BSA

Contains 0.09% sodium azide

Storage conditions 4° C

RRID AB_10984965

Product Specific Information

MA5-13643 targets Adenovirus Type 5 E1A in immunofluorescence, immunohistochemistry, immunoprecipitation and western blot applications and shows reactivity with Virus samples.

The MA5-13643 immunogen is adenovirus.

Target Information

Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). 49 human adenovirus serotypes have been discovered and divided into six subgroups, A to E, based on observation.

They are an important cause of respiratory illness, conjunctivitis, gastroenteritis, and have more recently been recognized as a potential cause of sexually transmitted diseases. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterized by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections.

It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated, causing disease. Adenovirus vectors, particularly those based on Ad5, have shown great promise for the development of gene therapy protocols and have been used for clinical purpose.

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Additional Information

100 µg
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